"Technology and Diagnosis: Novel techniques, methods, prospectives"

Abstract

In this review, a historical retrospection on the developments that shaped the fields of Biology andIn this review, a historical retrospection on the developments that shaped the fields of Biology andGenetics takes place, covering the past as well as the last sixty years more thoroughly. After that,key points in the progress of Cytogenetics are referred. Next, a comparative analysis betweendifferent methods used in detection of chromosomatic aberrations, reveals their advantages anddisadvantages. At the main part of this review, techniques are presented, providing historical facts,basic principles, working protocols and their most recent iterations. Every technique from basickaryotyping to the latest sequencing technologies is included. Also, non-invasive prenatal testing isdiscussedέΝThisΝreview’sΝgoalΝisΝtheΝstudyΝof progress in diagnostic technologies, their applicationsand the subsequent limitations. 

DERMOU Pantelis