"The role of stem cell replacement therapy cells in stroke"

Abstract

Stroke is one of the leading causes of morbidity and mortality worldwide.

To date, thrombectomy and thrombolysis are the appropriate methods of treatment, helping only in the acute phase but not in recovery. A stroke is a neurological entity in which many cellular subtypes are lost. Stem cell therapies appear to have a neuroprotective role, reducing the inflammatory response, as well as a neuroregenerative role by decreasing neuronal loss. Stem cell therapy has been proposed for improved repair of functional deficits, although the mechanisms behind their beneficial effects have not yet been understood.

Most studies may confirm the improvement of neurological function after the administration of various stem cells but many critical issues need to be addressed before clinical application.

ANAGNOSTOU Nikoletta