Bio-behavioral effects of psychotropics such as amphetamine, caffeine, cocaine and recently ketamine, cannabinoids and alcohol in rodents. Appropriate models in order to study, at a translational level, CNS disorders and their neurobiological substrates including anxiety/depression, drug abuse and schizophrenia.
Mechanisms underlying the behavioral and neurobiological effects of psychotropics such as cannabinoids, alcohol, ketamine, d-amphetamine, cocaine, and caffeine
Pharmacological evaluation (screening) of drugs/substances with CNS activity
Modeling of CNS disorders such as depression, psychosis and drugs of abuse
Definition of specific phenotypes (including individual differences) which characterized by certain behavioral outcomes and accompanied by respective neurobiological indices
Coupling with clinical studies aiming to the relationship between personality traits and the neurobiology of mental illness focusing on patients with a first psychotic episode and depression.