Objectives of the course: The Modern Histology is taught as a combination of Classical Morphology with new knowledge in the areas of Molecular Morphology (immunohistochemistry, in situ hybridization) and Cellular Biology.

The Histology I (Microscopic Anatomy) is the study of microscopic structures of the human body (tissues, cells, cell organelles), their relationships and their functions. The Modern Histology is the combination of Descriptive and Functional Histology of basic tissues. The Modern Histology also incorporates new knowledge from the fields of Molecular Histology (based on concepts of Cell Biology, Molecular Biology, Biochemistry and Physiology). The methods used by Histology is a) the light microscopy (tissues, cells), with the light microscope, b) electron microscopy (tissues, cells , cell organelles) with an electron microscope (magnification much greater compared with the light microscope) and c) the techniques Molecular Histology (immunohistochemistry and immunofluorescence enabling the detection of protein in direct correlation with the cell morphology and in situ hybridization allows the detection of nucleic acids (DNA or RNA) in direct correlation with the cellular morphology). In addition to modern Molecular Histology used cell culture techniques, protein isolation techniques and protein electrophoresis, Western blot and other modern molecular techniques.

Contents of the course: Introduction to Histology, Cell membrane, nucleus, organelles, cytoskeleton , Epithelial tissue , Classic Connective Tissue, Adipose tissue, Cartilage tissue, Bone tissue, Muscle tissue, Nervous tissue, Blood -Hematopoiesis, Circulatory System.

The laboratory practice include:
The histological and cytological study of the Epithelial tissue, the Connective tissue, the Adipose tissue, the Cartilage tissue, the Bone tissue, the Muscle tissue, the Nervous tissue, the Blood and the Circulatory system using the light microscope.

Mode and outcomes of teaching: The course is composed of lectures at the amphitheater and laboratory practice in groups of students.

At the end of the course the students should be able to:

• Know the Cytological and Histological terminology of basic tissues
• Know the microscopic structure and the correlation between microscopic structure and function of cell organelles, cells and basic tissues
• Know the basic principles of operation and use of the light microscope
• Identify and describe microscopic histological structures (tissues, cells) and describe the important microscopic features that allow the differentiation between different cellular and tissue structures.

Hours of training per student: 104

Semester: 1st

ECTS: 8