"Flow-cytometric approch to the diagnosis of T-lymphomas"

Abstract

Due to the rapid development of flow cytometry technology in various medical disciplines and fields, the following postgraduate thesis was completed. In particular, the main topic of lymphomas and especially of T-lymphomas, which their heterogeneity and their cytochemistry are complex and unknown in many cases, will be analyzed in 6 chapters independently and explicitly related to each other.

The first chapters will present the general data of the cells and the forms of pathological cells in the various subgroups of lymphomas. It will then describe how the machine of flow cytometer works and its principle of method . The order in which the topics will be presented is the function of normal blood cells and how they behave in pathological conditions. Also, to understand how flow cytometer works in these fields and its valuable help in prognosis, early diagnosis and effective treatment of lymphomas and more specifically of T-lymphomas. In the last two chapters, there are 10 incidents of different types of T-lymphomas, in full picture when diagnosed by flow cytometry, histological examination and further molecular techniques for additional diagnostic value. Also, the latest literature data on therapies and the further development of flow cytometry will be presented.

Finally, the work will conclude with the conclusions from the author and the scientists who have dealt with the clarification of the major issue of T-lymphocytes and recorded at work under the rules governing patients' personal rights

FLOROU Athina