Scope: teaching of different endocrine gland disorders based on common pathogenetic mechanisms so that the student may better understand the clinical features of diseases and syndromes that may affect multiple endocrine glands.

Course Syllabus:

1. Organ-specific autoimmunity

• principles
• polyglandular autoimmune syndrome (type I, II, III)
• autoimmune thyroid disease
• autoimmune diabetes mellitus (type 1, LADA)

2. Endocrine gland Hyperplasia/Neoplasia

• mulpiple endocrine neoplasia syndrome (type 1 and type 2)
• nodular thyroid disease
• adrenal incidentaloma

3. Target organ resistance to hormone actions

• steroid/sex hormone resistance
• thyroid hormone resistance
• peptide hormone resistance

4. Deficiency of enzymes of hormonogenesis - hormone metabolism

• deficiency of steroidogenesis enzymes
• deficiency of enzymes of thyroid hormone synthesis
• deficiency of enzymes of hormone metabolism

5. Disorders of energy/glucose homeostasis

• the role of fatty tissue on energy homeostasis
• lipodystrophies
• insulin resistance -type 2 diabetes

6. Disorders of bone metabolism

• hormonal regulation of bone metabolism
• vitamin D – pleiotropic actions
• osteomalacia – osteoporosis

Teaching format and outcomes: At the end of each teaching module, presented with the use of electronic aids, a number of relevant clinical cases will be presented and discussed. This will enable the student to obtain an integrated view of the different clinical entities. In parallel, those students who may be interested are given the option to present a review of the literature in a topic of their choice, related to the field of endocrinology and diabetes. At the end of the teaching program, these projects are presented by the students to their teachers and fellow students.

Hours of training per student: 26

From the 10th Semester

ECTS: 2